Description

2-(4-Isobutoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate and chemical building block. This compound is valued for its role as a key precursor in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the research and development of new pesticides and herbicides, leveraging its quinoline-based structure.
• Organic Synthesis Reagent: Serves as a versatile acyl chloride reagent for introducing the 2-(4-isobutoxyphenyl)-8-methylquinoline-4-carbonyl moiety into more complex molecular architectures.
• Material Science Precursor: Potential use in the development of organic electronic materials and functional dyes due to its conjugated quinoline system.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-(4-Isobutoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160254-61-4
Molecular Formula	C22H22ClNO2
Molecular Weight	367.87 g/mol
Synonyms	8-Methyl-2-[4-(2-methylpropoxy)phenyl]quinoline-4-carbonyl chloride; 2-(4-Isobutyloxyphenyl)-8-methyl-4-quinolinecarbonyl chloride; 2-(4-Isobutoxyphenyl)-8-methylquinoline-4-carboxylic acid chloride; Quinoline-4-carbonyl chloride, 2-[4-(2-methylpropoxy)phenyl]-8-methyl-; CAS 1160254-61-4
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Isobutoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.