Description

8-Methyl-2-(4-Propoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters because it serves as a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty functional materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential anticancer, antimicrobial, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the quinoline scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials, such as OLEDs or conductive polymers.
• Ligand and Catalyst Development: Employed to synthesize complex chelating ligands for catalytic systems or metal-organic frameworks (MOFs).
• Fluorescent Probe Synthesis: Utilized as a core structure for developing sensitive fluorescent dyes and molecular probes used in bioimaging and diagnostics.
• Custom Chemical Synthesis: Provides a versatile starting point for contract research organizations (CROs) and fine chemical companies producing bespoke compounds for client projects.

Basic Information

Product Name	8-Methyl-2-(4-Propoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160254-55-6
Molecular Formula	C21H20ClNO2
Molecular Weight	353.84 g/mol
Synonyms	4-Quinolinecarbonyl chloride, 8-methyl-2-[4-(propoxy)phenyl]-; 2-(4-Propoxyphenyl)-8-methylquinoline-4-carbonyl chloride; 8-Methyl-2-(4-propoxy-phenyl)-quinoline-4-carbonyl chloride; 1160254-55-6; 8-Methyl-2-(4-propoxyphenyl)-4-quinolinecarbonyl chloride; 2-(4-Propoxyphenyl)-8-methyl-4-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 8-Methyl-2-(4-Propoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.