Description

2-(4-Ethoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate belonging to the quinoline family. This compound is critical for the synthesis of advanced pharmaceutical compounds and functional materials due to its versatile carbonyl chloride functional group. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research for developing small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring complex heterocyclic structures.
• Material Science Research: Serves as a precursor for creating functional organic materials, including ligands for metal-organic frameworks (MOFs) and optoelectronic materials.
• Chemical Biology Probes: Employed in the development of fluorescent probes and biochemical tools due to the quinoline scaffold's photophysical properties.
• Academic & Industrial R&D: Essential reagent for synthetic organic chemists in universities, contract research organizations (CROs), and corporate R&D laboratories.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals used in dyes, pigments, and advanced polymer additives.

Basic Information

Product Name	2-(4-Ethoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160254-49-8
Molecular Formula	C20H16ClNO2
Molecular Weight	337.80 g/mol
Synonyms	8-Methyl-2-(4-ethoxyphenyl)quinoline-4-carbonyl chloride; 2-(4-Ethoxyphenyl)-8-methyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(4-ethoxyphenyl)-8-methyl-; 1160254-49-8; 2-(p-Ethoxyphenyl)-8-methylquinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Ethoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.