Description

2-(4-Bromophenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is valued for its role as a key synthon in the synthesis of complex molecules, particularly in medicinal chemistry and materials science. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the quinoline scaffold's bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport or host materials in optoelectronic devices.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic synthesis and methodology development.
• Dye and Pigment Industry: Acts as an intermediate for the production of specialized quinoline-based dyes and colorants.

Basic Information

Product Name	2-(4-Bromophenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160254-37-4
Molecular Formula	C17H11BrClNO
Molecular Weight	360.63 g/mol
Synonyms	8-Methyl-2-(4-bromophenyl)quinoline-4-carbonyl chloride; 2-(4-Bromophenyl)-8-methyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(4-bromophenyl)-8-methyl-; 1160254-37-4; 2-(p-Bromophenyl)-8-methylquinoline-4-carbonyl chloride; 8-Methyl-2-(p-bromophenyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-8-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.