Description

2-(4-Isopropylphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate belonging to the quinoline family. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides, leveraging the quinoline scaffold's bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced organic electronic materials, such as OLEDs or sensors.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands or organocatalysts for asymmetric synthesis.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized quinoline-based dyes and colorants.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	2-(4-Isopropylphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160254-25-0
Molecular Formula	C21H18ClNO
Molecular Weight	335.83 g/mol
Synonyms	8-Methyl-2-[4-(1-methylethyl)phenyl]-4-quinolinecarbonyl chloride; 2-(4-Isopropylphenyl)-8-methyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-[4-(1-methylethyl)phenyl]-8-methyl-; 2-(p-Isopropylphenyl)-8-methylquinoline-4-carbonyl chloride; 8-Methyl-2-(4-propan-2-ylphenyl)quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Isopropylphenyl)-8-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.