Description

2-(3,4-Dimethylphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-value, reactive organic intermediate belonging to the quinoline family. This compound is crucial for its role as a key building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) agents, anti-infectives, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides, leveraging the quinoline scaffold's bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced organic electronic materials, such as OLEDs and sensors.
• Ligand and Catalyst Development: Employed to create complex chelating ligands for metal catalysis in asymmetric synthesis and other fine chemical processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring this specific molecular architecture.

Basic Information

Product Name	2-(3,4-Dimethylphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160254-17-0
Molecular Formula	C19H16ClNO
Molecular Weight	309.79 g/mol
Synonyms	8-Methyl-2-(3,4-dimethylphenyl)quinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(3,4-dimethylphenyl)-8-methyl-; 2-(3,4-Dimethylphenyl)-8-methyl-4-quinolinecarbonyl chloride; 2-(3,4-Dimethylphenyl)-8-methylquinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dimethylphenyl)-8-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.