Description

8-Methyl-2-(2-Methylphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its role as a key building block for constructing complex heterocyclic frameworks, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors, antimicrobials, and anticancer agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers, dyes, and photoactive materials.
• Chemical Synthesis: Acts as a versatile acyl chloride reagent for introducing the 8-methyl-2-(2-methylphenyl)quinoline-4-carbonyl moiety into more complex molecular architectures.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	8-Methyl-2-(2-Methylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160254-09-0
Molecular Formula	C19H14ClNO
Molecular Weight	307.77 g/mol
Synonyms	4-Quinolinecarbonyl chloride, 8-methyl-2-(2-methylphenyl)-; 2-(2-Methylphenyl)-8-methylquinoline-4-carbonyl chloride; 8-Methyl-2-o-tolylquinoline-4-carbonyl chloride; 2-(2-Methylphenyl)-8-methyl-4-quinolinecarbonyl chloride; (8-Methyl-2-(2-methylphenyl)quinolin-4-yl)methanoyl chloride
EINECS	Contact for details

Quality Control

Our 8-Methyl-2-(2-Methylphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.