Description

8-Methyl-2-(5-Methyl-2-Thienyl)Quinoline-4-Carbonyl Chloride is a high-value, reactive chemical intermediate characterized by its quinoline-thiophene hybrid structure and acid chloride functional group. This compound matters for its role as a critical building block in the synthesis of complex molecules, enabling the introduction of the quinoline pharmacophore into target structures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for anti-infective, anti-inflammatory, or anticancer research.
• Agrochemical Synthesis: Used in the development of new pesticides, herbicides, or fungicides where the quinoline moiety can confer specific biological activity.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of advanced organic electronic materials, such as OLEDs or conductive polymers.
• Ligand and Catalyst Development: Employed to construct complex nitrogen-containing ligands for metal catalysis and coordination chemistry.
• Fluorescent Probe Synthesis: Utilized to build quinoline-based fluorophores for sensing and bio-imaging applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	8-Methyl-2-(5-Methyl-2-Thienyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160254-03-4
Molecular Formula	C₁₇H₁₄ClNOS
Molecular Weight	323.81 g/mol
Synonyms	4-Quinolinecarbonyl chloride, 8-methyl-2-(5-methyl-2-thienyl)-; 2-(5-Methylthiophen-2-yl)-8-methylquinoline-4-carbonyl chloride; 8-Methyl-2-(5-methylthien-2-yl)quinoline-4-carboxylic acid chloride; 1160254-03-4; 8-Methyl-2-(5-methyl-2-thienyl)-4-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 8-Methyl-2-(5-Methyl-2-Thienyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.