Description

2-(4-Ethoxyphenyl)-6-Methylquinoline-4-Carbonyl Chloride is a high-purity organic intermediate, specifically an acid chloride derivative of a quinoline carboxylic acid. This compound is valued for its role as a critical building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, leveraging the quinoline scaffold's bioactivity.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Fluorescent Dye & Sensor Development: The quinoline core can be utilized to develop new fluorescent probes and chemosensors for analytical applications.
• Organic Synthesis Building Block: The reactive carbonyl chloride group enables facile amide bond formation, making it a versatile reagent for constructing peptide mimetics and other complex amides.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and contract research organizations (CROs) exploring new chemical entities.

Basic Information

Product Name	2-(4-Ethoxyphenyl)-6-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160253-81-5
Molecular Formula	C20H18ClNO2
Molecular Weight	339.82 g/mol
Synonyms	6-Methyl-2-(4-ethoxyphenyl)quinoline-4-carbonyl chloride; 2-(4-Ethoxyphenyl)-6-methyl-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 2-(4-ethoxyphenyl)-6-methyl-; 4-Quinolinecarbonyl chloride, 2-(4-ethoxyphenyl)-6-methyl-; 1160253-81-5
EINECS	Contact for details

Quality Control

Our 2-(4-Ethoxyphenyl)-6-Methylquinoline-4-Carbonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.