Description

6-Methyl-2-(2-Methylphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its role as a versatile acyl chloride building block, enabling the efficient introduction of the quinoline-4-carbonyl moiety into complex molecular architectures. This compound is critically needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the quinoline scaffold is a common pharmacophore.
• Material Science Research: Serves as a precursor for creating functional organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Chemical Biology Probes: Employed in the development of fluorescent tags and molecular probes for biochemical and diagnostic applications.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory synthesis in university and corporate research laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	6-Methyl-2-(2-Methylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160253-39-3
Molecular Formula	C19H16ClNO
Molecular Weight	309.79 g/mol
Synonyms	2-(2-Methylphenyl)-6-methylquinoline-4-carbonyl chloride; 6-Methyl-2-o-tolylquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 6-methyl-2-(2-methylphenyl)-; 2-(2-Methylphenyl)-6-methyl-4-quinolinecarbonyl chloride; 6-Methyl-2-(2-methylphenyl)-4-quinolinecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 6-Methyl-2-(2-Methylphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.