Description

2-(5-Ethyl-2-Thienyl)-6-Methylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is critical for the synthesis of complex organic molecules, offering a versatile building block for constructing novel chemical architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinoline-based drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in amide coupling reactions, peptide synthesis, and the construction of heterocyclic compounds due to its reactive acid chloride group.
• Agrochemical Research: Serves as a starting material for developing novel crop protection agents and herbicides with quinoline scaffolds.
• Material Science: Employed in the research and development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for methodological studies and creating libraries of novel chemical entities.

Basic Information

Product Name	2-(5-Ethyl-2-Thienyl)-6-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160253-35-9
Molecular Formula	C₁₇H₁₄ClNOS
Molecular Weight	323.81 g/mol
Synonyms	6-Methyl-2-(5-ethyl-2-thienyl)quinoline-4-carbonyl chloride; 2-(5-Ethylthiophen-2-yl)-6-methylquinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 2-(5-ethyl-2-thienyl)-6-methyl-; 1160253-35-9; 2-(5-Ethyl-2-thienyl)-6-methyl-4-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(5-Ethyl-2-Thienyl)-6-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.