Description

6-Bromo-2-(5-Methyl-2-Thienyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical building block designed for advanced synthetic applications. Its core value lies in its reactive acid chloride group and complex heterocyclic structure, enabling precise molecular construction in demanding research and development. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists engaged in the synthesis of novel quinoline-based active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and other biologically active quinoline derivatives.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the quinoline-thiophene scaffold.
• Material Science: Serves as a monomer or functionalizing agent for creating advanced organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Synthesis: Acts as a versatile electrophile in amide coupling reactions, facilitating the rapid assembly of complex amide libraries for screening.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis or as a core structure for organocatalysts.
• Academic and R&D: A critical reagent for methodological studies in organic chemistry and for exploring new reaction pathways involving halogenated heterocycles.

Basic Information

Product Name	6-Bromo-2-(5-Methyl-2-Thienyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160253-03-1
Molecular Formula	C₁₆H₉BrClNOS
Molecular Weight	378.67 g/mol
Synonyms	6-Bromo-2-(5-methylthiophen-2-yl)quinoline-4-carbonyl chloride; 2-(5-Methyl-2-thienyl)-6-bromo-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 6-bromo-2-(5-methyl-2-thienyl)-; 1160253-03-1; 6-Bromo-2-(5-methyl-2-thienyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(5-Methyl-2-Thienyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.