Description

3-Ethoxy-4-[(4-Methylbenzyl)Oxy]Benzoyl Chloride is a specialized benzoyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its reactive acid chloride functional group, which facilitates efficient coupling reactions to form esters and amides under mild conditions. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules in active pharmaceutical ingredient (API) and crop protection agent development.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring complex aromatic ether scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where specific benzoyl-based structures are required.
• Liquid Crystal & OLED Material Research: Serves as a building block for synthesizing novel organic electronic materials and liquid crystal compounds due to its rigid, substituted benzoyl core.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functional monomers, where it can introduce photoreactive or cross-linking groups.
• Fine Chemical & Custom Synthesis: A versatile reagent for contract research organizations (CROs) and custom synthesis facilities performing complex multi-step organic transformations.
• Academic & Industrial R&D: Fundamental research tool in medicinal chemistry and material science laboratories for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	3-Ethoxy-4-[(4-Methylbenzyl)Oxy]Benzoyl Chloride
CAS No.	1160250-78-1
Molecular Formula	C17H17ClO3
Molecular Weight	304.77 g/mol
Synonyms	4-[(4-Methylbenzyl)oxy]-3-ethoxybenzoyl chloride; 3-Ethoxy-4-[(4-methylphenyl)methoxy]benzoyl chloride; Benzoyl chloride, 3-ethoxy-4-[(4-methylbenzyl)oxy]-; p-Methylbenzyl 3-ethoxy-4-hydroxybenzoate chloride (precursor form); ETMB-Benzoyl Chloride (abbrev.); 1160250-78-1 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our production of 3-Ethoxy-4-[(4-Methylbenzyl)Oxy]Benzoyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP and ISO 9001 compliant manufacturing upon request for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when dispensing to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.