Description

5-Bromo-2-[(2-Chloro-4-Fluorobenzyl)Oxy]Benzoyl Chloride is a high-purity, multi-functional organic intermediate of significant importance in modern synthetic chemistry. Its core value lies in its reactive benzoyl chloride and halogenated aromatic structure, making it a versatile building block for constructing complex molecules with precise functionality. This compound is primarily needed by research and development laboratories and production facilities in the pharmaceutical and agrochemical industries for the synthesis of advanced active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where its halogenated benzyloxy moiety contributes to biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling, modifying, or immobilizing biomolecules in probe and assay development.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) requiring high-fidelity halogenated aromatic compounds.

Basic Information

Product Name	5-Bromo-2-[(2-Chloro-4-Fluorobenzyl)Oxy]Benzoyl Chloride
CAS No.	1160250-64-5
Molecular Formula	C14H8BrCl2FO2
Molecular Weight	378.02 g/mol
Synonyms	5-Bromo-2-[(2-chloro-4-fluorobenzyl)oxy]benzoyl chloride; 2-[(2-Chloro-4-fluorobenzyl)oxy]-5-bromobenzoyl chloride; Benzoyl chloride, 5-bromo-2-[(2-chloro-4-fluorobenzyl)oxy]-; 5-Bromo-2-(2-chloro-4-fluorobenzyloxy)benzoyl chloride
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-[(2-Chloro-4-Fluorobenzyl)Oxy]Benzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis of the acid chloride functional group. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.