Description

5-Bromo-2-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive benzoyl chloride functional group and halogenated aromatic structure. This compound is essential for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of targeted small-molecule therapeutics. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for oncology and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated aromatic core for bioactivity.
• Chemical Synthesis: Serves as a versatile electrophile in coupling reactions (e.g., amidation, esterification) to introduce the 5-bromo-2-[(4-fluorobenzyl)oxy]benzoyl moiety.
• Material Science Precursor: Employed in the research and development of specialty polymers and liquid crystals.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Item	Details
Product Name	5-Bromo-2-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride
CAS No.	1160250-07-6
Molecular Formula	C15H11BrClFO2
Molecular Weight	357.60 g/mol
Synonyms	5-Bromo-2-[(4-fluorobenzyl)oxy]benzoyl chloride; 2-[(4-Fluorobenzyl)oxy]-5-bromobenzoyl chloride; 5-Bromo-2-(4-fluorobenzyloxy)benzoyl chloride; Benzoyl chloride, 5-bromo-2-[(4-fluorophenyl)methoxy]-; (5-Bromo-2-{[(4-fluorophenyl)methyl]oxy}phenyl)methanone chloride
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.