Description

4-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride CAS NO 1160249-58-0 is a high-purity, reactive benzoyl chloride derivative featuring a fluorobenzyloxy substituent. This compound serves as a critical pharmaceutical intermediate and organic synthesis building block, enabling the introduction of a specific aromatic ether moiety into target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorinated aromatic structure enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for mesogens and electron-transport materials in display and lighting technologies.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polyesters and polyamides with unique thermal and optical properties.
• Peptide & Protein Modification: Utilized as an acylating agent for modifying amino acid side chains in biochemical research and bioconjugation.
• Chemical Research & Development: A versatile reagent for introducing the 4-[(4-fluorobenzyl)oxy]benzoyl group in medicinal chemistry and material science explorations.

Basic Information

Item	Detail
Product Name	4-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride
CAS No.	1160249-58-0
Molecular Formula	C14H10ClFO2
Molecular Weight	264.68 g/mol
Synonyms	4-[(4-Fluorobenzyl)oxy]benzoyl chloride; p-[(p-Fluorobenzyl)oxy]benzoyl chloride; 4-(4-Fluorobenzyloxy)benzoyl chloride; (4-Fluorobenzyloxy)benzoyl chloride; 4-Fluorobenzyl 4-chlorocarbonylphenyl ether; Benzoyl chloride, 4-[(4-fluorobenzyl)oxy]-; 1160249-58-0
EINECS	Contact for details

Quality Control

Every batch of 4-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride is manufactured under cGMP-like conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of pharmaceutical and advanced chemical industries. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.