Description

4,5,6,7,8,9-Hexahydrocycloocta[B]Thiophene-2-Carbonyl Chloride is a specialized, high-purity organic intermediate featuring a reactive acid chloride functional group on a saturated cyclooctathiophene scaffold. This compound is critical for introducing the unique hexahydrocycloocta[b]thiophene moiety into target molecules, enabling advanced material and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring complex, saturated heterocycles.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection, leveraging its unique structure for bioactivity.
• Material Science Research: Serves as a precursor for functionalized organic semiconductors, ligands for catalysis, or monomers for specialty polymers.
• Chemical Biology Probes: Employed to create labeled compounds or molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific advanced intermediates.

Basic Information

Product Name	4,5,6,7,8,9-Hexahydrocycloocta[B]Thiophene-2-Carbonyl Chloride
CAS No.	1160249-25-1
Molecular Formula	C11H13ClOS
Molecular Weight	228.74 g/mol
Synonyms	Hexahydrocycloocta[b]thiophene-2-carbonyl chloride; Perhydrocycloocta[b]thiophene-2-carbonyl chloride; Cycloocta[b]thiophene-2-carbonyl chloride, 4,5,6,7,8,9-hexahydro-; 2-Carbonyl chloride-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene
EINECS	Contact for details

Quality Control

Every batch of 4,5,6,7,8,9-Hexahydrocycloocta[B]Thiophene-2-Carbonyl Chloride is produced and analyzed under strict quality management protocols. We ensure compliance with relevant industry standards for advanced chemical intermediates. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and IR spectroscopy, is provided with each shipment to guarantee consistent quality and reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.