Description

4-Methyl-5-Phenylthiophene-2-Carbonyl Chloride is a high-purity organic intermediate characterized by its reactive acid chloride functional group. This compound matters as a critical building block for synthesizing more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel thiophene-based active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides with thiophene cores.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed to create specialized ligands for metal catalysis and organocatalysts.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Fundamental research tool in organic chemistry for exploring new heterocyclic compounds and reaction methodologies.

Basic Information

Product Name	4-Methyl-5-Phenylthiophene-2-Carbonyl Chloride
CAS No.	1160249-12-6
Molecular Formula	C13H9ClOS
Molecular Weight	248.72 g/mol
Synonyms	5-Phenyl-4-methylthiophene-2-carbonyl chloride; 4-Methyl-5-phenyl-2-thiophenecarbonyl chloride; 2-Thenoyl chloride, 4-methyl-5-phenyl-; 4-Methyl-5-phenylthiophene-2-carboxylic acid chloride; 2-Thiophenecarbonyl chloride, 4-methyl-5-phenyl-; 1160249-12-6; 4-Methyl-5-phenyl-2-thienoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methyl-5-Phenylthiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.