Description

5-Methyl-4-Phenylthiophene-3-Carbonyl Chloride is a high-purity, reactive organic intermediate characterized by its acid chloride functional group. This compound is a critical building block in advanced organic synthesis, enabling the efficient formation of amide and ester bonds. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those containing thiophene and phenyl motifs for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive site for structural diversification.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the creation of molecular probes and labeled compounds for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	5-Methyl-4-Phenylthiophene-3-Carbonyl Chloride
CAS No.	1160248-98-5
Molecular Formula	C13H9ClOS
Molecular Weight	248.72 g/mol
Synonyms	4-Phenyl-5-methylthiophene-3-carbonyl chloride; 3-Thiophenecarbonyl chloride, 4-phenyl-5-methyl-; 5-Methyl-4-phenyl-3-thiophenecarboxylic acid chloride; 4-Phenyl-5-methyl-3-thiophenecarboxylic acid chloride; 5-Methyl-4-phenylthiophene-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 5-Methyl-4-Phenylthiophene-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.