Description

4-Ethyl-5-Methylthiophene-3-Carbonyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. Its value lies in its role as a key building block for constructing complex heterocyclic molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed to create specialized ligands for metal catalysis and organocatalysis in asymmetric synthesis.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the pharmaceutical industry.

Basic Information

Product Name	4-Ethyl-5-Methylthiophene-3-Carbonyl Chloride
CAS No.	1160248-82-7
Molecular Formula	C9H11ClOS
Molecular Weight	202.70 g/mol
Synonyms	3-Carbonyl chloride, 4-ethyl-5-methylthiophene; 4-Ethyl-5-methylthiophene-3-carboxylic acid chloride; 4-Ethyl-5-methyl-3-thiophenecarbonyl chloride; 5-Methyl-4-ethylthiophene-3-carbonyl chloride; Thiophene-3-carbonyl chloride, 4-ethyl-5-methyl-; 4-Ethyl-5-methylthiophene-3-carboxyl chloride
EINECS	Contact for details

Quality Control

Our 4-Ethyl-5-Methylthiophene-3-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically verified by HPLC, GC, NMR, and IR spectroscopy. We adhere to relevant industry standards for fine chemical intermediates to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.