Description

(9R)- 9-Isothiocyanato-6'-Methoxy-Cinchonan CAS NO 1155843-55-2 is a high-purity, chiral alkaloid derivative, structurally related to cinchona alkaloids, which are renowned for their utility as organocatalysts and chiral ligands. This compound matters for its role in facilitating asymmetric synthesis, enabling the production of enantiomerically pure intermediates critical for pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require advanced chiral building blocks for drug discovery and process development.

Application

• Chiral Organocatalyst in asymmetric carbon-carbon and carbon-heteroatom bond-forming reactions.
• Chiral Ligand for transition metal catalysis in enantioselective hydrogenation and oxidation processes.
• Key Intermediate in the synthesis of novel pharmaceutical compounds and active pharmaceutical ingredients (APIs).
• Research Chemical for developing new methodologies in academic and industrial organic chemistry laboratories.
• Building Block for creating chiral stationary phases used in analytical chromatography (HPLC, SFC).
• Template Molecule in medicinal chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	(9R)- 9-Isothiocyanato-6'-Methoxy-Cinchonan
CAS No.	1155843-55-2
Molecular Formula	C₂₁H₂₃N₃O₂S
Molecular Weight	381.49 g/mol
Synonyms	(9R)-9-Isothiocyanato-6'-methoxycinchonan; 6'-Methoxy-9-isothiocyanatocinchonan (9R)-; Cinchonan, 9-isothiocyanato-6'-methoxy-, (9R)-; (R)-9-Isothiocyanato-6'-methoxycinchonan; 9-Isothiocyanato-6'-methoxycinchonan (R-enantiomer); (9R)-9-Isothiocyanatocinchonan-6'-methylether; (R)-9-Isothiocyanato-6'-methoxycinchonidine derivative
EINECS	Contact for details

Quality Control

Our (9R)- 9-Isothiocyanato-6'-Methoxy-Cinchonan is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.