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3,4,6-Tri-o-Acetyl-p-Nitrophenyl 2-Azido-2-Deoxy-α-D-Galactopyranoside CAS NO 1147438-51-4


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CAS No.:1147438-51-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3,4,6-Tri-o-Acetyl-p-Nitrophenyl 2-Azido-2-Deoxy-α-D-Galactopyranoside is a specialized, high-purity glycosylation building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise, activated intermediates for constructing complex carbohydrate-based molecules. It is primarily utilized in the development of glycoconjugates, glycan arrays, and novel therapeutic agents within the pharmaceutical and biotechnology sectors.

Application

  • Glycoconjugate Synthesis: A key activated intermediate for the chemical and enzymatic synthesis of complex oligosaccharides and glycoproteins.
  • Pharmaceutical Research: Used in the development of carbohydrate-based vaccines, drug delivery systems, and diagnostic agents.
  • Chemical Biology Probes: Serves as a precursor for "click chemistry" applications, enabling the labeling and study of biological systems via its azido functional group.
  • Glycan Array Fabrication: Employed to create libraries of defined carbohydrates for high-throughput screening of protein-carbohydrate interactions.
  • Enzyme Substrate Studies: Acts as a substrate or inhibitor in studies of glycosyltransferases and glycosidases.
  • Material Science: Used in the surface functionalization of materials to introduce bioactive carbohydrate motifs.

Basic Information

Product Name 3,4,6-Tri-o-Acetyl-p-Nitrophenyl 2-Azido-2-Deoxy-α-D-Galactopyranoside
CAS No. 1147438-51-4
Molecular Formula C19H22N4O11
Molecular Weight 482.40 g/mol
Synonyms p-Nitrophenyl 2-azido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranoside; 2-Azido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranosyl p-nitrophenyl; α-D-Galactopyranoside, p-nitrophenyl 2-azido-2-deoxy-3,4,6-tri-O-acetyl-; PNPTriOAc-α-GalNAz; Activated GalNAz donor; Glycosyl donor for click chemistry
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Quality Control

Our 3,4,6-Tri-o-Acetyl-p-Nitrophenyl 2-Azido-2-Deoxy-α-D-Galactopyranoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at lower temperatures (-20°C) to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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