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3,4,6-Tri-o-Acetyl-p-Nitrophenyl 2-Azido-2-Deoxy-α-D-Galactopyranoside CAS NO 1147438-51-4
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CAS No.:1147438-51-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3,4,6-Tri-o-Acetyl-p-Nitrophenyl 2-Azido-2-Deoxy-α-D-Galactopyranoside is a specialized, high-purity glycosylation building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise, activated intermediates for constructing complex carbohydrate-based molecules. It is primarily utilized in the development of glycoconjugates, glycan arrays, and novel therapeutic agents within the pharmaceutical and biotechnology sectors.
Application
- Glycoconjugate Synthesis: A key activated intermediate for the chemical and enzymatic synthesis of complex oligosaccharides and glycoproteins.
- Pharmaceutical Research: Used in the development of carbohydrate-based vaccines, drug delivery systems, and diagnostic agents.
- Chemical Biology Probes: Serves as a precursor for "click chemistry" applications, enabling the labeling and study of biological systems via its azido functional group.
- Glycan Array Fabrication: Employed to create libraries of defined carbohydrates for high-throughput screening of protein-carbohydrate interactions.
- Enzyme Substrate Studies: Acts as a substrate or inhibitor in studies of glycosyltransferases and glycosidases.
- Material Science: Used in the surface functionalization of materials to introduce bioactive carbohydrate motifs.
Basic Information
| Product Name | 3,4,6-Tri-o-Acetyl-p-Nitrophenyl 2-Azido-2-Deoxy-α-D-Galactopyranoside |
| CAS No. | 1147438-51-4 |
| Molecular Formula | C19H22N4O11 |
| Molecular Weight | 482.40 g/mol |
| Synonyms | p-Nitrophenyl 2-azido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranoside; 2-Azido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranosyl p-nitrophenyl; α-D-Galactopyranoside, p-nitrophenyl 2-azido-2-deoxy-3,4,6-tri-O-acetyl-; PNPTriOAc-α-GalNAz; Activated GalNAz donor; Glycosyl donor for click chemistry |
| EINECS | Contact for details |
Quality Control
Our 3,4,6-Tri-o-Acetyl-p-Nitrophenyl 2-Azido-2-Deoxy-α-D-Galactopyranoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at lower temperatures (-20°C) to maintain optimal stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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