Description

Guanosine Hydrate is a high-purity nucleoside building block essential for biochemical research and pharmaceutical synthesis. This compound serves as a critical precursor in the development of nucleotide analogs, antiviral agents, and molecular biology reagents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleic acid chemistry and therapeutic development.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of antiviral drugs (e.g., nucleoside reverse transcriptase inhibitors) and anticancer agents.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, polymerase chain reaction (PCR), and studies of RNA metabolism and function.
• Cell Culture Media: Component in specialized cell culture formulations and media supplements for studying cellular processes.
• Diagnostic Reagent Manufacturing: Raw material for producing diagnostic kits and reagents that detect or quantify nucleic acids.
• Nucleotide Synthesis: Fundamental building block for the chemical and enzymatic synthesis of oligonucleotides and modified nucleotides.
• Cosmetic & Skincare Actives: Ingredient in high-end cosmetic formulations for its potential skin-conditioning properties.

Basic Information

Product Name	Guanosine Hydrate
CAS No.	1143525-19-2
Molecular Formula	C₁₀H₁₃N₅O₅ • xH₂O
Molecular Weight	283.24 (Anhydrous basis)
Synonyms	Guanosine Monohydrate; 9-β-D-Ribofuranosylguanine Hydrate; 2-Amino-1,9-dihydro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6H-purin-6-one Hydrate; D-Ribose, 2-amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one, monohydrate; Guanine Riboside Hydrate; Vernine Hydrate
EINECS	Contact for details

Quality Control

Our Guanosine Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent controls for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with relevant guidelines for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	5.0% - 8.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm
Specific Rotation	-60° to -70° (c=1 in 0.1N NaOH)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.