Description

2,3-Dimethoxy-6-(Trimethylsilyl)Pyridine is a high-value, functionalized pyridine derivative characterized by its dimethoxy and trimethylsilyl protecting groups. This compound serves as a versatile and critical advanced pharmaceutical intermediate and organosilicon building block for complex organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to construct novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting the central nervous system.
• Ligand Precursor: Used in the preparation of specialized ligands for catalysis, including those in cross-coupling reactions.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of novel organic electronic materials and silicon-containing polymers.
• Agrochemical Synthesis: Intermediate for creating new generations of herbicides, fungicides, and insecticides with enhanced properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex molecules.

Basic Information

Product Name	2,3-Dimethoxy-6-(Trimethylsilyl)Pyridine
CAS No.	1131335-54-0
Molecular Formula	C₁₀H₁₇NO₂Si
Molecular Weight	211.33 g/mol
Synonyms	6-(Trimethylsilyl)-2,3-dimethoxypyridine; 2,3-Dimethoxy-6-(trimethylsilyl)pyridine; Pyridine, 2,3-dimethoxy-6-(trimethylsilyl)-; 2,3-Dimethoxy-6-trimethylsilylpyridine; TMS-Protected Dimethoxypyridine; (2,3-Dimethoxypyridin-6-yl)trimethylsilane
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dimethoxy-6-(Trimethylsilyl)Pyridine is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality system is designed to support cGMP requirements for advanced intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.