Description

1-(4-Chloro-2-(3-Methyl-1H-Pyrazol-1-Yl)Phenyl)-2,2,2-Trifluoroethanone is a high-value trifluoromethyl ketone derivative that serves as a critical building block in advanced organic synthesis. This compound is engineered to provide a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a precursor in the development of next-generation herbicides, fungicides, and insecticides, leveraging the stability of the trifluoromethyl group.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced materials with unique thermal or chemical resistance properties.
• Chemical Biology Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	1-(4-Chloro-2-(3-Methyl-1H-Pyrazol-1-Yl)Phenyl)-2,2,2-Trifluoroethanone
CAS No.	1125828-30-9
Molecular Formula	C₁₂H₈ClF₃N₂O
Molecular Weight	288.65 g/mol
Synonyms	1-[4-Chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]ethanone; 4-Chloro-2-(3-methyl-1H-pyrazol-1-yl)-α,α,α-trifluoroacetophenone; 1-(4-Chloro-2-(3-methylpyrazol-1-yl)phenyl)-2,2,2-trifluoroethanone; CAS 1125828-30-9
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-2-(3-Methyl-1H-Pyrazol-1-Yl)Phenyl)-2,2,2-Trifluoroethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.