Description

4-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]Benzoyl Chloride is a high-value, bifunctional organic intermediate featuring both a reactive benzoyl chloride and a chloromethyl-oxadiazole moiety. This compound matters for its versatility as a key building block in the synthesis of complex molecules, enabling the introduction of the oxadiazole heterocycle which is prized for its biological activity. It is primarily needed by pharmaceutical and agrochemical R&D departments for creating new active ingredients, as well as by specialty chemical manufacturers developing advanced materials and ligands.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or receptor modulation where the 1,2,4-oxadiazole ring is a key pharmacophore.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the oxadiazole scaffold.
• Chemical Biology & Proteomics: Serves as a versatile linker or coupling agent for bioconjugation, labeling proteins, or creating activity-based probes for target identification.
• Material Science Research: Employed in the creation of functional polymers, metal-organic frameworks (MOFs), or organic electronic materials where its dual functionality allows for precise structural control.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Item	Detail
Product Name	4-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]Benzoyl Chloride
CAS No.	1119450-88-2
Molecular Formula	C10H6Cl2N2O2
Molecular Weight	257.07 g/mol
Synonyms	4-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)benzoyl chloride; 3-(4-(Chlorocarbonyl)phenyl)-5-(chloromethyl)-1,2,4-oxadiazole; 4-(5-Chloromethyl-[1,2,4]oxadiazol-3-yl)-benzoyl chloride; Benzoyl chloride, 4-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]-; 1119450-88-2
EINECS	Contact for details

Quality Control

Our 4-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, it should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage and opened only in a moisture-free environment. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.