Description

5-Bromo-3-Methylpyridine-2-Carbonyl Chloride is a high-purity, reactive organic intermediate of significant importance in advanced synthetic chemistry. This compound serves as a critical building block for the construction of complex heterocyclic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research and development chemists, process development scientists, and manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its pyridine-based structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Essential for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic and Industrial R&D: A valuable reagent for exploratory chemistry in both university laboratories and corporate R&D centers.

Basic Information

Product Name	5-Bromo-3-Methylpyridine-2-Carbonyl Chloride
CAS No.	1114809-24-3
Molecular Formula	C8H5BrClNO
Molecular Weight	234.49 g/mol
Synonyms	2-Pyridinecarbonyl chloride, 5-bromo-3-methyl-; 5-Bromo-3-methylpicolinoyl chloride; 5-Bromo-3-methyl-2-pyridinecarboxylic acid chloride; 3-Methyl-5-bromopicolinoyl chloride; 5-Bromo-3-methylpyridine-2-carboxylic acid chloride; 1114809-24-3; 5-Br-3-Me-Py-2-COCl
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-Methylpyridine-2-Carbonyl Chloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to consistent quality and supply reliability supports your critical R&D and manufacturing timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended long-term storage temperature is 2-8°C. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.