Description

3-(4-Chlorophenyl)-5-Ethyl-1-Methyl-1H-Indole-2-Carbonyl Chloride is a high-purity, reactive indole-based intermediate essential for advanced organic synthesis. Its core value lies in its versatile carbonyl chloride functional group, enabling efficient coupling reactions to construct complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of anti-inflammatory and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the indole scaffold for biological activity.
• Material Science Research: Serves as a precursor for functionalized organic materials and specialty polymers requiring specific indole motifs.
• Academic & Contract Research: A valuable reagent for method development and exploring new chemical spaces in university and CRO laboratory settings.
• Peptide Mimetic Chemistry: Employed in the design and synthesis of peptidomimetics and other bioactive molecules that incorporate indole derivatives.

Basic Information

Product Name	3-(4-Chlorophenyl)-5-Ethyl-1-Methyl-1H-Indole-2-Carbonyl Chloride
CAS No.	1114597-24-8
Molecular Formula	C18H15Cl2NO
Molecular Weight	332.22 g/mol
Synonyms	5-Ethyl-1-methyl-3-(4-chlorophenyl)-1H-indole-2-carbonyl chloride; 1H-Indole-2-carbonyl chloride, 3-(4-chlorophenyl)-5-ethyl-1-methyl-; 3-(p-Chlorophenyl)-5-ethyl-1-methylindole-2-carbonyl chloride; 3-(4-Chlorophenyl)-5-ethyl-1-methylindole-2-carbonyl chloride; 1114597-24-8
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenyl)-5-Ethyl-1-Methyl-1H-Indole-2-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.