Description

8-Chloro-2’-β-C-Methyl Inosine is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the production of novel antiviral and anticancer therapeutics, particularly in the development of nucleotide-based prodrugs. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of next-generation active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of antiviral nucleotide analogs targeting hepatitis C virus (HCV) and other viral pathogens.
• Anticancer Drug Research: Used in the development of nucleoside-based chemotherapeutic agents that inhibit abnormal cellular proliferation.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleoside metabolism and polymerase function.
• Prodrug Synthesis: A crucial precursor for creating prodrug forms designed to enhance bioavailability and targeted delivery of nucleotide therapeutics.
• Reference Standard: Employed as an analytical standard in quality control and method development for API manufacturing.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleoside drug candidates.

Basic Information

Product Name	8-Chloro-2’-β-C-Methyl Inosine
CAS No.	1106012-39-8
Molecular Formula	C11H13ClN4O5
Molecular Weight	316.70 g/mol
Synonyms	8-Chloro-2'-C-methylinosine; 8-Chloro-2'-methylinosine; 2'-C-Methyl-8-chloroinosine; 8-Chloro-2'-β-C-methylinosine; 8-Cl-2'-C-Me-inosine; 8-Chloro-2'-deoxy-2'-methylinosine; Inosine, 8-chloro-2'-C-methyl-; 1106012-39-8
EINECS	Contact for details

Quality Control

Our 8-Chloro-2’-β-C-Methyl Inosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.