Description

(2,4-Difluoro-5-Iodo-Phenyl)-Methanol is a high-purity fluorinated and iodinated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated aromatic structure makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and pesticides where the difluoro and iodo substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystal compounds and charge-transport materials in organic light-emitting diodes (OLEDs) due to its electronic properties.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to build complex biaryl and conjugated systems.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating specialized chemical libraries.
• Positron Emission Tomography (PET) Tracer Precursor: Potential use in synthesizing fluorinated radioligands for medical imaging applications.

Basic Information

Product Name	(2,4-Difluoro-5-Iodo-Phenyl)-Methanol
CAS No.	1097626-21-5
Molecular Formula	C7H5F2IO
Molecular Weight	269.02 g/mol
Synonyms	5-Iodo-2,4-difluorobenzyl alcohol; (5-Iodo-2,4-difluorophenyl)methanol; 2,4-Difluoro-5-iodobenzyl alcohol; 1-(Hydroxymethyl)-5-iodo-2,4-difluorobenzene; α-Hydroxy-5-iodo-2,4-difluorotoluene
EINECS	Contact for details

Quality Control

Our (2,4-Difluoro-5-Iodo-Phenyl)-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.