Description

(R)-2-Bromo-1-(4-Fluorophenyl)Ethanol is a chiral building block of significant importance in modern synthetic organic chemistry. Its value lies in its role as a key intermediate for the synthesis of complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in pharmaceutical R&D and fine chemical production who require high-purity, enantiomerically pure intermediates for developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of potential drug candidates, especially in areas targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-inflammatory agents.
• Asymmetric Synthesis: Used in stereoselective reactions to construct complex molecular architectures with defined chirality, crucial for producing single-enantiomer drugs.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in enantioselective transformations.
• Agrochemical Research: Employed in the development of novel, enantiomerically pure pesticides and herbicides.
• Material Science: Potential monomer or building block for creating chiral polymers or advanced organic materials with specific optical properties.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	(R)-2-Bromo-1-(4-Fluorophenyl)Ethanol
CAS No.	1097211-38-5
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	(R)-2-Bromo-1-(4-fluorophenyl)ethanol; (R)-1-(4-Fluorophenyl)-2-bromoethanol; (R)-2-Bromo-1-(p-fluorophenyl)ethanol; (R)-α-Bromo-4-fluorobenzeneethanol; (1R)-2-Bromo-1-(4-fluorophenyl)ethan-1-ol; p-Fluoro-(R)-α-bromophenethyl alcohol; (R)-Bromo(4-fluorophenyl)methylcarbinol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Each batch of (R)-2-Bromo-1-(4-Fluorophenyl)Ethanol is characterized and tested to ensure high chemical and enantiomeric purity, typically meeting standards suitable for advanced pharmaceutical research. Certificates of Analysis (COA) detailing identity (IR, NMR), assay (HPLC), chiral purity (Chiral HPLC), and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.