Description

5-(2-Bromoacetyl)-1-Methyl-2,3-Dihydro-1H-Indol-2-One is a high-purity brominated indolone derivative serving as a critical advanced pharmaceutical intermediate (API intermediate) for the synthesis of complex bioactive molecules. Its unique structure, featuring a reactive bromoacetyl group fused to a methylated oxindole core, makes it an essential building block for medicinal chemistry research and process development. This compound is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams targeting novel therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probes: Serves as a starting material for developing enzyme inhibitors or receptor modulators used in biochemical assays.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for organic synthesis methodology development and novel heterocyclic compound exploration.

Basic Information

Product Name	5-(2-Bromoacetyl)-1-Methyl-2,3-Dihydro-1H-Indol-2-One
CAS No.	1094318-21-4
Molecular Formula	C11H10BrNO2
Molecular Weight	268.11 g/mol
Synonyms	1-Methyl-5-(2-bromoacetyl)indolin-2-one; 5-(Bromoacetyl)-1-methyl-2-indolinone; 5-(2-Bromoacetyl)-1-methylindolin-2-one; 1-Methyl-5-(bromoacetyl)oxindole; 5-Bromoacetyl-1-methyloxindole; 2-Oxo-1-methyl-5-(2-bromoacetyl)indoline; 1094318-21-4; 5-(2-Bromoacetyl)-1-methyl-2,3-dihydro-1H-indol-2-one
EINECS	Contact for details

Quality Control

Our 5-(2-Bromoacetyl)-1-Methyl-2,3-Dihydro-1H-Indol-2-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.