Description

3-(3-Fluoro-5-Methoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound serves as a critical building block in modern medicinal chemistry, particularly for the research and development of kinase inhibitors targeting various therapeutic areas. It is essential for pharmaceutical R&D teams, academic research institutions, and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) for oncology, immunology, and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of targeted kinase inhibitor drug candidates.
• Biochemical Research: Used as a reference standard or a core scaffold in structure-activity relationship (SAR) studies for drug discovery programs.
• API Development: Employed in the process development and scale-up manufacturing of novel active pharmaceutical ingredients (APIs).
• Academic Research: Serves as a valuable reagent in university and institutional labs for exploring new heterocyclic chemistry and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical companies with custom synthesis and development services.

Basic Information

Product Name	3-(3-Fluoro-5-Methoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No.	1092789-24-6
Molecular Formula	C₁₂H₁₀FN₅O
Molecular Weight	259.24 g/mol
Synonyms	3-(3-Fluoro-5-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(3-fluoro-5-methoxyphenyl)-; 1092789-24-6; 3-(3-Fluoro-5-methoxyphenyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidine; 4-Amino-3-(3-fluoro-5-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 3-(3-Fluoro-5-Methoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.