Description

3-Ethoxy-2,6-Difluorobenzylalcohol is a high-purity fluorinated benzyl alcohol derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the strategic placement of fluorine and ethoxy substituents, which are essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoroethoxy moiety can enhance bioavailability and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in advanced display technologies.
• Organic Electronic Materials: Intermediate in the production of fluorinated organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The benzyl alcohol group can be functionalized for use in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Protecting Group Chemistry: The alcohol functionality can be used to introduce protecting groups or serve as a handle for further synthetic elaboration in multi-step syntheses.

Basic Information

Product Name	3-Ethoxy-2,6-Difluorobenzylalcohol
CAS No.	1092461-28-3
Molecular Formula	C9H10F2O2
Molecular Weight	188.17 g/mol
Synonyms	(3-Ethoxy-2,6-difluorophenyl)methanol; 2,6-Difluoro-3-ethoxybenzyl alcohol; 1-(3-Ethoxy-2,6-difluorophenyl)methanol; Benzyl alcohol, 3-ethoxy-2,6-difluoro-; α-Hydroxymethyl-3-ethoxy-2,6-difluorobenzene
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-2,6-Difluorobenzylalcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.