Description

5-Chloro-2-(Trifluoromethoxy)Benzoylchloride is a high-value, multi-functional aromatic acid chloride intermediate. Its molecular structure, featuring both chloro and trifluoromethoxy substituents, makes it a critical building block for synthesizing advanced compounds with tailored properties. This product is essential for R&D chemists and process engineers in the pharmaceutical and agrochemical sectors seeking to develop novel active ingredients. Its reactivity enables efficient derivatization into amides, esters, and other key functional groups.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized aromatic cores in electronic and display materials.
• Polymer Chemistry: Employed as a monomer or cross-linking agent for producing high-performance polymers with specific thermal and chemical resistance.
• Organic Synthesis & R&D: A versatile reagent for academic and industrial research in developing new fluorinated compounds and complex organic molecules.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments requiring halogenated and fluorinated aromatic components.

Basic Information

Product Name	5-Chloro-2-(Trifluoromethoxy)Benzoylchloride
CAS No.	1092461-17-0
Molecular Formula	C8H3Cl2F3O2
Molecular Weight	273.01 g/mol
Synonyms	5-Chloro-2-(trifluoromethoxy)benzoyl chloride; 2-Chloro-α,α,α-trifluoro-p-anisoyl chloride; 5-Chloro-α,α,α-trifluoro-o-anisoyl chloride; Benzoyl chloride, 5-chloro-2-(trifluoromethoxy)-; 5-Chloro-2-trifluoromethoxybenzoyl chloride; 2-Trifluoromethoxy-5-chlorobenzoyl chloride; 1092461-17-0
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Trifluoromethoxy)Benzoylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting standards for research and production. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.