Description

n-[(1S)-1-(5-Fluoropyrimidin-2-Yl)Ethyl]-3-(5-Isopropoxy-1H-Pyrazol-3-Yl)-3H-Imidazo[4,5-B]Pyridin-5-Amine is a sophisticated heterocyclic organic compound designed for advanced research and development. This molecule is of significant interest due to its complex structure, which incorporates multiple pharmacologically relevant motifs, including a fluoropyrimidine and an imidazopyridine core. It serves as a critical intermediate or active pharmaceutical ingredient (API) building block for pharmaceutical companies and research institutions engaged in drug discovery programs, particularly in oncology and targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors.
• Oncology Research: Used in preclinical studies targeting specific cancer pathways due to its structural similarity to known bioactive molecules.
• Chemical Biology: Serves as a probe or tool compound for studying enzyme function and cellular signaling mechanisms.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for potential APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Employed in university laboratories for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	n-[(1S)-1-(5-Fluoropyrimidin-2-Yl)Ethyl]-3-(5-Isopropoxy-1H-Pyrazol-3-Yl)-3H-Imidazo[4,5-B]Pyridin-5-Amine
CAS No.	1079274-94-4
Molecular Formula	C19H19FN8O
Molecular Weight	394.41 g/mol
Synonyms	5-Amino-3-(5-isopropoxy-1H-pyrazol-3-yl)-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]imidazo[4,5-b]pyridine; (S)-N-(1-(5-Fluoropyrimidin-2-yl)ethyl)-3-(5-isopropoxy-1H-pyrazol-3-yl)-3H-imidazo[4,5-b]pyridin-5-amine; 3H-Imidazo[4,5-b]pyridin-5-amine, N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-3-(5-isopropoxy-1H-pyrazol-3-yl)-; CAS 1079274-94-4
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and MS. Specifications are designed to meet the rigorous demands of pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.