Description

4-Methoxy-3-(trifluoromethoxy)benzoyl chloride, 97% is a high-purity, functionalized benzoyl chloride derivative serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of methoxy and trifluoromethoxy substituents, which are instrumental for modulating the electronic and steric properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially those targeting central nervous system (CNS) disorders, due to the trifluoromethoxy group's ability to enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the specific substitution pattern contributes to biological activity and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for mesogenic compounds used in display technologies, leveraging its aromatic core and polar substituents.
• Polymer Chemistry: Acts as a monomer or modifying agent for introducing aromatic ester linkages and functional groups into specialty polymers.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation and other reactions to introduce the 4-methoxy-3-(trifluoromethoxy)benzoyl moiety into complex molecular architectures.
• Chemical Research & Development: A valuable tool for medicinal chemists and material scientists exploring structure-activity relationships (SAR) and new chemical entities.

Basic Information

Product Name	4-Methoxy-3-(trifluoromethoxy)benzoyl chloride, 97%
CAS No.	1070774-23-0
Molecular Formula	C9H6ClF3O3
Molecular Weight	254.59 g/mol
Synonyms	4-Methoxy-3-(trifluoromethoxy)benzoyl chloride; 3-(Trifluoromethoxy)-4-methoxybenzoyl chloride; 4-Methoxy-α,α,α-trifluoro-3-(trifluoromethoxy)benzeneacetyl chloride (common misnomer); Benzoyl chloride, 4-methoxy-3-(trifluoromethoxy)-; 4-Methoxy-3-trifluoromethoxybenzoyl chloride; 1070774-23-0; CAS 1070774-23-0
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-(trifluoromethoxy)benzoyl chloride, 97% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency meet the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) detailing specific results for assay, impurities, and other critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with water and strong bases. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.