Description

3-Cyano-5-Fluorobenzoyl Chloride is a high-purity, multi-functional organic intermediate of significant importance in advanced chemical synthesis. Its value lies in its dual reactive sites—the acid chloride and the cyano group—which enable efficient derivatization for creating complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and cyano-substituted aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of monomers for high-performance polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A versatile reagent for academic and industrial research in organic methodology development and medicinal chemistry.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis and scale-up projects.

Basic Information

Product Name	3-Cyano-5-Fluorobenzoyl Chloride
CAS No.	1064396-14-0
Molecular Formula	C8H3ClFNO
Molecular Weight	183.57 g/mol
Synonyms	5-Fluoro-3-cyanobenzoyl chloride; 3-Cyano-5-fluorobenzoic acid chloride; 5-Fluoroisophthalonitrile monoacid chloride; 3-Carbamoyl-5-fluorobenzoic acid chloride (tautomer); 1064396-14-0; 3-Fluoro-5-cyanobenzoyl chloride (isomer check); Benzoyl chloride, 3-cyano-5-fluoro-
EINECS	Contact for details

Quality Control

Our 3-Cyano-5-Fluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, store in a cool (2-8°C), dry, and well-ventilated place under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.