Description

4'-C-Methyl-4-Deoxyuridine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a key building block and intermediate in the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular DNA replication pathways. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of nucleoside-based therapeutics and molecular probes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of compounds targeting viral polymerases of viruses such as Hepatitis C Virus (HCV) and other RNA viruses.
• Oncology Research: Serves as a precursor for potential chemotherapeutic agents that inhibit DNA synthesis in rapidly dividing cells.
• Biochemical Tool: Employed in enzymatic studies to investigate substrate specificity and inhibition mechanisms of nucleoside kinases and other enzymes.
• Molecular Biology: Used in the synthesis of modified oligonucleotides for research into gene function and regulation.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.

Basic Information

Product Name	4'-C-Methyl-4-Deoxyuridine
CAS No.	1064364-21-1
Molecular Formula	C10H14N2O5
Molecular Weight	242.23 g/mol
Synonyms	4'-C-Methyl-4'-deoxyuridine; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 4'-Methyl-4'-deoxyuridine; 4'-C-Methyluridine derivative; 4'-Deoxy-4'-C-methyluridine; Modified Uridine Analog; Nucleoside Intermediate 1064364-21-1
EINECS	Contact for details

Quality Control

Our 4'-C-Methyl-4-Deoxyuridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.