Description

3-B-D-Ribofuranosyl-6-Hydroxymethyl-Furano[2,3-D]-Pyrimidin-2-One is a high-purity nucleoside analogue building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel antiviral and anticancer agents, enabling the exploration of targeted therapeutic mechanisms. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in the development of nucleoside-based drugs and prodrugs. The compound's unique furanopyrimidine scaffold offers a versatile platform for creating molecules with specific biological activity profiles.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for novel antiviral and anticancer nucleoside analogues.
• Antiviral Drug Research: Used in the development of potential therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating prodrugs and targeted chemotherapeutic agents.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor in nucleoside metabolism pathways.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-B-D-Ribofuranosyl-6-Hydroxymethyl-Furano[2,3-D]-Pyrimidin-2-One
CAS No.	1058167-74-0
Molecular Formula	C₁₄H₁₆N₂O₇
Molecular Weight	324.29 g/mol
Synonyms	6-(Hydroxymethyl)-3-β-D-ribofuranosylfuro[2,3-d]pyrimidin-2(3H)-one; 3-β-D-Ribofuranosyl-6-(hydroxymethyl)furo[2,3-d]pyrimidin-2(3H)-one; 6-Hydroxymethyl-3-β-D-ribofuranosylfuro[2,3-d]pyrimidin-2-one; Nucleoside Furanopyrimidinone Derivative; Furo[2,3-d]pyrimidine Nucleoside; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-B-D-Ribofuranosyl-6-Hydroxymethyl-Furano[2,3-D]-Pyrimidin-2-One is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity suitable for research and development applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.