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1-Azido-23-Bromo-3,6,9,12,15,18,21-Heptaoxatricosane CAS NO 1056969-61-9
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CAS No.:1056969-61-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-Azido-23-Bromo-3,6,9,12,15,18,21-Heptaoxatricosane is a specialized bifunctional polyethylene glycol (PEG) derivative, featuring both azide and bromo terminal groups for advanced synthetic applications. This compound is engineered for high-yield, selective conjugation reactions, particularly in click chemistry and polymer science, enabling the reliable construction of complex molecular architectures. It is a critical intermediate for researchers and manufacturers in pharmaceuticals, bioconjugation, and materials science who require precise, modular, and efficient coupling strategies.
Application
- Bioconjugation & Click Chemistry: The azide group enables efficient, copper-catalyzed azide-alkyne cycloaddition (CuAAC) for labeling biomolecules, antibodies, and proteins.
- Pharmaceutical Linker: Serves as a versatile heterobifunctional crosslinker for constructing antibody-drug conjugates (ADCs) and prodrugs.
- Polymer & Dendrimer Synthesis: Acts as a key monomer or chain extender for creating functionalized PEG-based polymers, hydrogels, and dendritic structures.
- Surface Modification: Used to introduce reactive azide or bromo functionalities onto nanoparticles, biosensors, and chromatographic media for further derivatization.
- Materials Science: Facilitates the development of smart materials, drug delivery systems, and biocompatible coatings with tailored properties.
- Chemical Biology Probes: Essential for synthesizing activity-based probes and affinity labels for target identification and validation in drug discovery.
Basic Information
| Product Name | 1-Azido-23-Bromo-3,6,9,12,15,18,21-Heptaoxatricosane |
| CAS No. | 1056969-61-9 |
| Molecular Formula | C₂₀H₃₉BrN₃O₇ |
| Molecular Weight | 529.44 g/mol |
| Synonyms | Azido-PEG7-Bromide; Bromo-PEG7-Azide; α-Azido-ω-bromo-hepta(ethylene glycol); 23-Bromo-3,6,9,12,15,18,21-heptaoxatricosan-1-azide; Br-PEG7-N₃; Heterobifunctional PEG Azide Bromide; PEG7 Azide Bromide; N₃-PEG7-Br |
| EINECS | Contact for details |
Quality Control
Our 1-Azido-23-Bromo-3,6,9,12,15,18,21-Heptaoxatricosane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance for sensitive applications like bioconjugation. Certificates of Analysis (COA) detailing purity, identity, and functional group integrity are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep container tightly sealed in a desiccated environment when not in use.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 0.5% |
| Functional Group Assay (Azide) | ≥ 90% |
| Functional Group Assay (Bromo) | ≥ 90% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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