Description

Cyt387, Msoh Salt is a high-purity, small molecule compound of significant interest in pharmaceutical research and development. This compound is valued for its role as a potent and selective inhibitor of Janus Kinase (JAK) enzymes, which are key targets in modulating immune and inflammatory responses. It is primarily utilized by researchers and manufacturers in the life sciences sector for preclinical studies, drug discovery programs, and the development of novel therapeutic agents targeting autoimmune diseases, myeloproliferative neoplasms, and other conditions.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the development of JAK inhibitor therapies.
• Biochemical Assays: Used as a selective inhibitor in enzymatic and cellular assays to study JAK/STAT signaling pathways and their role in disease mechanisms.
• Preclinical Studies: Employed in in vitro and in vivo models to investigate efficacy, pharmacokinetics, and toxicology profiles for potential new drugs.
• Academic Research: A key tool for universities and research institutions exploring immunology, oncology, and inflammatory disease biology.
• Process Chemistry & Scale-up: Used as a starting material or intermediate in the synthetic route for producing candidate drugs under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	Cyt387, Msoh Salt
CAS No.	1056636-07-7
Molecular Formula	C₂₂H₂₂N₆O₂ • CH₄O₃S
Molecular Weight	502.56 g/mol
Synonyms	Momelotinib methanesulfonate salt; CYT387 methanesulfonate; (1E)-1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}methylene-2-(1H-indazol-3-yl)-1,2-dihydro-3H-benz[e]indol-3-one methanesulfonate; 3-((1E)-2-(1H-Indazol-3-yl)-3-oxo-2,3-dihydro-1H-benzo[e]indol-1-ylidene)methyl)-1H-pyrrolo[2,3-b]pyridine methanesulfonate; GS-0387; JAK Inhibitor CYT387 mesylate
EINECS	Contact for details

Quality Control

Our Cyt387, Msoh Salt is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant quality guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange solid powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.