Description

(3-Amino-2-Fluorophenyl)Methanol CAS NO 1051899-73-0 is a high-purity aromatic building block featuring both amino and fluorinated substituents, making it a versatile intermediate for advanced synthesis. Its molecular structure is critical for introducing specific functional groups and modifying physicochemical properties in target molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the effects of fluorine substitution on aromatic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns.

Basic Information

Product Name	(3-Amino-2-Fluorophenyl)Methanol
CAS No.	1051899-73-0
Molecular Formula	C7H8FNO
Molecular Weight	141.14 g/mol
Synonyms	2-Fluoro-3-aminobenzyl alcohol; (3-Amino-2-fluorophenyl)methanol; 3-Amino-2-fluorobenzyl alcohol; 2-Fluoro-3-aminophenylmethanol; 1-(3-Amino-2-fluorophenyl)methanol; Benzenemethanol, 3-amino-2-fluoro-; 3-Amino-2-fluoro-benzenemethanol
EINECS	Contact for details

Quality Control

Our (3-Amino-2-Fluorophenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent oxidation and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.