Description

Butanamide, n-(3-Azidopropyl)-4-[3-[6-(4-Methyl-1-Piperazinyl)[2,6'-Bi-1H-Benzimidazol]-2'-Yl]Phenoxy]- is a sophisticated, high-value organic intermediate featuring a complex heterocyclic benzimidazole core functionalized with an azide group. This compound matters for its role as a critical building block in advanced pharmaceutical research and materials science, enabling click chemistry and targeted molecular assembly. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and specialty chemical sectors for developing novel therapeutics, diagnostic probes, and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors and targeted cancer therapies.
• Bioconjugation & Probe Development: The reactive azide group enables efficient, site-specific conjugation to alkyne-modified biomolecules (antibodies, proteins, peptides) via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for creating diagnostic and imaging agents.
• Polymer & Materials Science: Serves as a functional monomer or cross-linker for synthesizing advanced polymers with tailored optical, electronic, or mechanical properties.
• Chemical Biology Research: Used as a tool compound to label and study biological systems, facilitating target identification and pathway analysis.
• Agrochemical Research: Intermediate in the development of new-generation crop protection agents with specific modes of action.

Basic Information

Product Name	Butanamide, n-(3-Azidopropyl)-4-[3-[6-(4-Methyl-1-Piperazinyl)[2,6'-Bi-1H-Benzimidazol]-2'-Yl]Phenoxy]-
CAS No.	1049722-30-6
Molecular Formula	C32H36N10O2
Molecular Weight	592.70 g/mol
Synonyms	N-(3-Azidopropyl)-4-[3-[6-(4-methylpiperazin-1-yl)-[2,6'-bi-1H-benzimidazol]-2'-yl]phenoxy]butanamide; 4-[3-[6-(4-Methyl-1-piperazinyl)[2,6'-bi-1H-benzimidazol]-2'-yl]phenoxy]-N-(3-azidopropyl)butanamide; UNII-8F8Q8F9K4R; 8F8Q8F9K4R; Azido-functionalized benzimidazole piperazine derivative; Click chemistry benzimidazole intermediate
EINECS	Contact for details

Quality Control

This high-purity intermediate is manufactured under strict GMP-like conditions to ensure batch-to-batch consistency for sensitive research and development applications. Every lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR, and MS for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is light-sensitive and may be hygroscopic. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from strong acids and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.