Description

[3,4-Bis(Trifluoromethoxy)Phenyl]Methanol is a high-value fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters because its unique structure, featuring two trifluoromethoxy groups, imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery, particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy groups improve biological activity and environmental persistence profiles.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal mixtures for advanced display technologies.
• Polymer Modification: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Electronics: Utilized in the synthesis of charge-transport materials or emissive layers for OLEDs (Organic Light-Emitting Diodes).
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new fluorination methodologies.

Basic Information

Product Name	[3,4-Bis(Trifluoromethoxy)Phenyl]Methanol
CAS No.	1048922-46-8
Molecular Formula	C10H6F6O3
Molecular Weight	288.14 g/mol
Synonyms	(3,4-Bis(trifluoromethoxy)phenyl)methanol; 1-[3,4-Bis(trifluoromethoxy)phenyl]methanol; [3,4-Bis(trifluoromethoxy)benzyl] alcohol; α-Hydroxymethyl-3,4-bis(trifluoromethoxy)benzene; 3,4-Bis(trifluoromethoxy)benzenemethanol; 3,4-Bis(trifluoromethoxy)benzyl alcohol; 1048922-46-8; (3,4-Di(trifluoromethoxy)phenyl)methanol
EINECS	Contact for details

Quality Control

Our [3,4-Bis(Trifluoromethoxy)Phenyl]Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.