Description

Gsk2110183B CAS NO 1047645-82-8 is a potent and selective small molecule inhibitor primarily used in biochemical and pharmacological research. This compound is valued for its high specificity in modulating key cellular signaling pathways, making it a critical tool for target validation and mechanism-of-action studies. It is essential for researchers and developers in the pharmaceutical and biotechnology sectors focused on oncology, immunology, and metabolic disease research.

Application

• Biochemical Research: Used as a selective kinase inhibitor in enzymatic assays to study signal transduction mechanisms.
• Pharmaceutical R&D: Serves as a key reference standard and lead compound in drug discovery programs for targeted therapies.
• Cell Biology Studies: Applied in cell-based assays to investigate the effects of pathway inhibition on proliferation, apoptosis, and differentiation.
• Preclinical Development: Utilized in animal model studies to evaluate the efficacy and pharmacokinetics of novel therapeutic candidates.
• Academic Research: A fundamental reagent for universities and research institutes exploring cellular regulation and disease models.

Basic Information

Item	Detail
Product Name	Gsk2110183B
CAS No.	1047645-82-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GSK2110183B; GSK-2110183B; 1047645-82-8; (S)-2-(1-(4-Amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one; Afuresertib; Akt inhibitor GSK2110183B
EINECS	Contact for details

Quality Control

Our Gsk2110183B is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.