Description

N2-Phenylacetyl-7'-Oh-n-Trityl-Morpholino Guanine CAS NO 1044241-98-6 is a high-purity, advanced nucleoside derivative specifically designed for pharmaceutical research and development. This compound serves as a critical building block and key intermediate in the synthesis of novel antiviral and anticancer agents, particularly within the field of oligonucleotide and prodrug chemistry. It is essential for R&D teams in pharmaceutical, biotechnology, and fine chemical synthesis sectors requiring precise molecular scaffolds for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of modified nucleoside analogs for antiviral and anticancer drug candidates.
• Oligonucleotide Synthesis: Used in the research and development of morpholino-based antisense oligonucleotides and other gene-silencing therapeutics.
• Prodrug Development: Serves as a protected guanine derivative for creating targeted prodrugs with enhanced bioavailability and stability.
• Biochemical Research: Employed as a standard or reagent in studies investigating nucleotide metabolism, enzyme inhibition, and nucleic acid chemistry.
• Fine Chemical Synthesis: A versatile building block for custom synthesis and the preparation of complex, high-value specialty chemicals.

Basic Information

Item	Detail
Product Name	N2-Phenylacetyl-7'-Oh-n-Trityl-Morpholino Guanine
CAS No.	1044241-98-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	7'-Hydroxy-N2-phenylacetyl-N-tritylmorpholino guanine; N-Trityl-morpholino guanine phenylacetate derivative; N2-PAc-7'-OH-N-Trt-morpholino-G; Guanosine morpholino derivative, N2-protected; CAS 1044241-98-6; Advanced guanine nucleoside intermediate; Protected morpholino nucleoside
EINECS	Contact for details

Quality Control

Every batch of N2-Phenylacetyl-7'-Oh-n-Trityl-Morpholino Guanine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.