Description

(2-Fluoro-4-Iodophenyl)Methanol is a versatile fluorinated and iodinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in providing a bifunctional handle for constructing complex molecular architectures, where the reactive benzylic alcohol and the halogenated aromatic ring enable precise derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials through cross-coupling reactions and further functionalization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis, such as Suzuki-Miyaura and Sonogashira cross-couplings.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers where fluorine and iodine substitution modulates electronic properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for imaging and diagnostic applications due to the presence of the iodine atom.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	(2-Fluoro-4-Iodophenyl)Methanol
CAS No.	1039646-78-0
Molecular Formula	C7H6FIO
Molecular Weight	252.03 g/mol
Synonyms	(2-Fluoro-4-iodophenyl)methanol; 2-Fluoro-4-iodobenzyl alcohol; 4-Iodo-2-fluorobenzyl alcohol; (2-Fluoro-4-iodo-phenyl)-methanol; 1-(Hydroxymethyl)-2-fluoro-4-iodobenzene; α-Hydroxy-2-fluoro-4-iodotoluene; Benzenemethanol, 2-fluoro-4-iodo-
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-Iodophenyl)Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.