Description

Pf-03654746, 4-Methylbenzenesulfonate (1:1) is a high-purity chemical salt, specifically the tosylate salt form of a pharmaceutical intermediate or active compound. This material is critical for ensuring consistent reactivity, stability, and bioavailability in advanced synthetic processes. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development and production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Process Chemistry: Used in scale-up and optimization of synthetic routes due to its defined salt form, which can improve handling and purification characteristics.
• Chemical Research: Employed in academic and industrial R&D for exploring new chemical entities and reaction methodologies.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	Pf-03654746, 4-Methylbenzenesulfonate (1:1)
CAS No.	1039399-17-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PF-03654746 Tosylate; PF03654746 4-Methylbenzenesulfonate; 4-Methylbenzenesulfonic acid compound with PF-03654746 (1:1); Tosic acid salt of PF-03654746; Benzenesulfonic acid, 4-methyl-, compd. with PF-03654746 (1:1); PF-03654746 p-Toluenesulfonate; PF-03654746 TsOH salt
EINECS	Contact for details

Quality Control

Our Pf-03654746, 4-Methylbenzenesulfonate (1:1) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical development. Certificates of Analysis (COA) with detailed batch-specific data are provided to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.