Description

Mk-4827 (Tosylate) is a high-purity, small molecule chemical compound with the CAS registry number 1038915-73-9. This compound is valued as a critical intermediate and research tool in advanced pharmaceutical development and life science research. It is primarily sought after by R&D teams and process chemists in the pharmaceutical, biotechnology, and fine chemical synthesis sectors for its specific biological activity and utility in creating novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel drug candidates targeting specific biological pathways.
• Biochemical Assay Development: Used as a reference standard or active component in high-throughput screening (HTS) and in vitro biological testing.
• Preclinical Studies: Employed in pharmacological and toxicological evaluations to understand compound efficacy and safety profiles.
• Process Chemistry & Scale-up: Acts as a building block for the optimization and commercial-scale production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and molecular biology.
• Contract Research Organizations (CROs): Supplied to CROs supporting drug discovery programs for client pharmaceutical companies.

Basic Information

Product Name	Mk-4827 (Tosylate)
CAS No.	1038915-73-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MK-4827 Tosylate; MK4827 Tosylate; Niraparib Tosylate; (S)-2-(4-(4-(3,4-Dihydro-4-oxo-1-phthalazinyl)phenyl)-1-piperazinyl)-2-(4-fluorophenyl)-N-methylacetamide 4-methylbenzenesulfonate; ZEJULA Tosylate salt; MK 4827 Tosylate salt
EINECS	Contact for details

Quality Control

Our Mk-4827 (Tosylate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect this light-sensitive material from moisture and environmental contaminants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities <2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	<1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.